Despina Kourti was born in Rhodes. She studied Law and Film in Athens. Her first short, The Doll (2014) premiered at the Athens IFF. Her second short, Ourania (2017), won four awards at the Drama International Short Film Festival and the script prize of the Athens IFF. She was supported by the 1st Artworks program of the Niarchos Foundation. Her short film Old West (2020) had its national premieres at the Drama and the Athens International Short Film Festivals and its international premiere at the Short Shorts Film Festival 2021. Her new short film, Numb, is in post-production.